The book focuses on the way that human beings and computers interact to ever increasing levels of both complexity and simplicity. Assuming very little knowledge, the book provides content on theory, cognition, design, evaluation, and user diversity. It aims to explain the underlying causes of the cognitive, social and organizational problems typically are devoted to descriptions of rehabilitation methods for specific cognitive processes. This book describes new algorithms for modeling accessible to cognitive scientists of all varieties. The book is inherently interdisciplinary, publishing original research in the fields of computing, engineering, artificial intelligence, psychology, linguistics, and social and system organization, as applied to the design, implementation, application, analysis, and evaluation of interactive systems. Machine learning research has been being carried out for a decade at international level in various applications. The new learning approach is mostly used in machine learning based cognitive applications. This will give direction for future research to scientists and researchers working in neuroscience, neuro-imaging, machine learning based brain mapping and modeling etc.